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Latest Reports

Intralipid

Intralipid TM 10%
Fat Emulsion for intravenous use


Intralipid 10% :
1000 ml of the emulsion contains: Purified soybean oil 100 g, purified egg phospholipids, glycerol anhydrous, sodium hydroxide, water for injections.

pH: Approximately 8
Osmolarity: 260 mosm/L
Energy content: 4.6 MJ (1100 kcal) / 1000 ml
Organic phosphate content: 15 mmol / 1000 ml

Indications:
Indicated to supply calorie and essential fatty acid
  • For the patients in ICU, pre-and post-operative care
  • For the patients with burns, sepsis, trauma, cancer, pancreatitis, gastrointestinal disease, liver disease, pregnancy, renal failure
  • As home parenteral nutrition

Dosage and Administration :
1 gm triglycerides corresponds to 10 ml Intralipid 10%.
Age Category Dose
Adult 1 ml/min (20 drops/min) for the first 15 to 30 minutes. If no unwanted reactions occur, the infusion rate may be increased to 2 ml/min(40 drops/min). Maximum dose is 500 ml for first day and should not exceed 3 gm triglycerides/kg/day for following day.
Children 0.1ml/min (2 drops/min)for the first 10 to 15 minutes. If no unwanted reactions occur, the infusion rate may be increased to 1 ml/Kg/hours. Do not exceed a daily dosage of 3 gm triglycerides/kg.
Infants 0.5g/kg/day(5 ml/kg/day). Maximum dosage is 3 gm/kg/24 hours.

Contra-indications :
INTRALIPID is contraindicated in patients with acute shock and in patients with severe hyperlipemia. Severe liver insufficiency. Hemophagocytotic syndrome. Hypersensitivity to egg-, soya- or peanut protein or to any of the active substances or excipients.

Pregnancy and lactation:
No adverse reactions connected with pregnancy and lactation have been reported.

Hepatic & Renal Impairment : Intrilipid can be given to supply energy and EFA in patient with hepatic and renal impairment with precaution.

Special precautions for storage: Store below 25°C. Do not freeze.

Presentation: :
Intralipid 10% is available in 500 ml glass bottle.